By a translocation at the genetic level, retin-a-cream acts on the promyelocytes which are hybrid receptors for retinoic acid.
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Hi naz, all tretinoin retin-a creams can cause irritation and dryness, as well as increased sensitivity to sunlight.
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I use a balm cleanser and a washcloth to take it off, but i realized that my skin actually started to sting as i used cerave hydrating as my second cleanser, and i attributed to the increased sensitivity to retin-a.
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i first started using retin-a about 4 years ago i am now 15 .